RAF Typhoon FGR4s have conducted a mission with French aircraft in a combined operation on an hidden munitions depot in Syrian territory operated by the Islamic State group (IS), per a report from the British defence ministry.
The facility, pinpointed through reconnaissance, was thought to be storing arms and explosives, the release indicated, and was positioned in hills just above Palmyra in the heart of Syria.
"Our fighter planes used laser-guided Paveway IV weapons to hit a several access tunnels leading to the depot... preliminary assessments suggest the objective was successfully hit," the MoD said.
There was no evidence of any harm to civilians in the strike late on Saturday and every plane involved made a safe return, the MoD added.
The Typhoon FGR4s were supported by a Voyager aerial refuelling aircraft.
The Islamic State group - referred to as the so-called Islamic State - enforced militant control over large swathes of Iraq and Syria before its territorial defeat in 2019.
"This action demonstrates the UK's leading role, and commitment to work closely with our partners, to stamp out any revival of Daesh and their harmful and extremist ideologies in the region," the British Defence Secretary John Healey said.
RAF aircraft have conducted patrols over Syria to "deter any attempted resurgence" of Islamic State following its defeat at the Baghuz confrontation in 2019, the MoD reported.
"I want to thank the personnel of British forces participating in this mission for their professionalism and their valour," the Defence Secretary said. "They were part of a great many UK service members deployed over Christmas and New Year. This operation, to eliminate militants who pose a risk to our safety, highlights how UK forces are prepared to act, throughout the year, ensuring Britain's security within its borders and powerful internationally."
Last December, the United States armed forces conducted what it described as a "major assault" targeting Islamic State objectives in the country, following an assault resulted in the deaths of two US servicemembers and a civilian linguist in the Palmyra area.
The UN reports IS still maintains between 5,000 and 7,000 combatants in both countries.